Question

4) What is the concept of age-related damage according to the bioengineering paradigm? (100 words)

Answer 1

Ageing causes accumulation of free radicals inside the cells. It also causes the accumulation of dysfunctional or toxic proteins inside the cells. It also causes the accumulation of silent mutations that result in sensitization of relevant proteins to oxidative damage as inborn predisposition to ageing and it’s related diseases.
With the increase in the age there will be increase in the oxidatively damaged proteins accumulated inside the cells which will result in the morbidity and becoming prone to get diseases and even mortality. Thus, ageing results in age-related cellular and tissue degradation that results in the disturbance in the homeostasis of the body, which causes malfunction, morbidity and later death that is caused by the in born structural and functional links.
Bioengineering is the discipline of doing repair of damaged tissues and or organs and replacing the dysfunctional organs or tissues in the place of damaged or non functional tissues and organs. As per the bioengineering paradigm the damage to the tissues occurs with the increase in the age of the persons. These damaged tissues or organs can be repaired or replaced by using bioengineering methods of tissue repair or transplantation and organ repair or transplantation.