Question

Select the true statements about zymogens.

Proteolytic enzymes are initially synthesized as zymogens to prevent off‑target activity.

Activation of zymogens through proteolytic cleavage is a reversible process.

Zymogens are inactive precursors that are cleaved to activate an enzyme.

Proteolytic cleavage at a specific site on the zymogen causes conformational changes that expose the active site of the enzyme.

Protease enzymes are the only enzymes activated by proteolytic cleavage.

Answer 1

Ans : Proteolytic cleavage at specific site on the zymogen cause configurational changes that reveal the active site of the enzyme.

Zymogens are known as pro enzyme ,it is inactive precursor of enzyme. Zymogen require proteolytic activity for revealing active site for enzyme reactions.