Question

A loss-of-function mutation in which of the following would have the same effect as a gain-of-function...

A loss-of-function mutation in which of the following would have the same effect as a gain-of-function mutation in Ras?

A.
Crk

B.
Csk

C.
Myc

D.
NF1

E.
Ab

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Answer #1

A loss-of-function mutation in which of the following would have the same effect as a gain-of-function mutation in Ras?

D) NF1

Neurofibromin 1 (NF1) is a human gene that is located on chromosome 17. NF1 is responsible to code for neurofibromin. When Ras-Nf1 complex can be assembled, active Ras can able to bind in the groove that exists in the neurofibromin catalytic domain.

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