What are “multi-reads”, and what are the transcriptome assembly problems associated with them?
What are “multi-reads”, and what are the transcriptome assembly problems associated with them?
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Answer :-Multi-mapped reads are sequences that map the genome more than once, for example, because there are multiple copies of a gene, such as precursors for tRNA.Such methods have a number of drawbacks, including: depends on existing knowledge of genome sequence; cross-hybridization lead to high background levels and limited dynamic detection range due to both background and signal saturation.
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What are “multi-reads”, and what are the transcriptome assembly
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