Question

what is the common mechanism for the drugs used to treat nematode parasires such as ivermectin?

a. they create an inflammation state inhospitable to nematode survival

b. they bind a molecular probe to the nematodes surface allowing the immune system to find and destroy it.

c. they release a chemical into circulation that is only toxic to the nematode so it dies when it consumes it

d. they aft as a GABA agonist paralyzing the nematode allowing them to be passed out in the feces

Answer 1

Answer: D

Overview: Ivermectin is believed to work as an agonist for the neurotransmitter gamma-aminobutyric acid (GABA). It disrupts the GABA mediated central nervous system neurosynaptic transmission. Alternatively, it also binds to the selective glutamate-gated chloride ion channels in muscle cells of invertebrates and allows an influx of chloride ions causing paralysis of the worms.