1) Which of the following functions within both the ER lumen and in the cytosol? A....
1) Which of the following functions within both the ER lumen and in the cytosol?
A. Hac1P
B. Ire1
C. PDI
D. P54SRP
E. Ubiquitin ligase
2.)Which of the following would be likely to cause an otherwise normal secretory protein to be ERADicated?
- A. BiP cannot exchange ADP for ATP
- B. Signal peptidase is inactivated
- C. Dislocon is inactivated
- D. (a) & (b)
- E. (a) & (c)
- F. (b) & (c)
- G. (a) (b) & (c) would likely to cause an otherwise normal secretory protein to be ERADicated
- H. None of the above would likely to cause an otherwise normal secretory protein to be ERADicated
Homework Answers
As per HomeworkLib policy Question 1 answer is
1) Which of the following functions within both the ER lumen and in the cytosol?
A. Hac1P
B. Ire1
C. PDI
D. P54SRP
E. Ubiquitin ligase
Ans 1. B IRe1
Add Answer to:
1) Which of the following functions within both the ER lumen and
in the cytosol?
A....
1. During the process of translating a protein into the lumen of the rough ER, the...
1. During the process of translating a protein into the lumen of the rough ER, the signal recognition particle (SRP) binds to both the signal sequence and the signal peptidase. the signal sequence and the SRP receptor. the start codon and the small ribosomal subunit. the start codon and the SRP receptor. 2. Each of the following modification processes takes place in the nucleus of a eukaryotic cell EXCEPT addition of a 5’ cap. addition of a poly-A tail. mRNA...
Which of the following statements describing the import of proteins into the nucleus is correct? Answers...
Which of the following statements describing the import of proteins into the nucleus is correct? Answers A-D A Transport into the nucleus requires the activity of a G protein. B The receptor for nuclear proteins is found in the cytosol and travels into the nucleus with the protein being transported o С Proteins destined for the nucleus are transported in a fully-folded conformation. D These statements are all correct. o You are interested in a water-soluble protein that functions within...
Which of the following proteins would NOT have the matched signal sequence? A. ER retention signal:...
Which of the following proteins would NOT have the matched signal sequence? A. ER retention signal: protein disulfide isomerase (PDI) B. ER signal sequence: Sec61 C. Peroxisome import signal: Catalase D. Mitochondrial Matrix signal sequence: Isocitrase dehydrogenase (part of TCA cycle) E. Thylakoid signal sequence: TIC and TOC
Which protein modification does NOT take place in the ER lumen? A. Polyubiquitylation &nbs
Which protein modification does NOT take place in the ER lumen? A. Polyubiquitylation B. N-linked glycosylation C. Cysteine bridge formation D. chaperone-mediated folding E. GPI anchoring 2. Which of these Eukaryotic proteins is least likely to exhibit an ER import sequence during translation? A. Glutathione B. CFTR C. Protein disulfide isomerase D. Acetylcholine receptor E. Na+-K+-ATPase 3. Which function is NOT attributed correctly to either smooth ER (SER) or rough ER (RER)?...
If the lipid bilayer in Section B represents the ER membrane, which part of the protein...
If the lipid bilayer in Section B represents the ER membrane, which part of the protein is found INSIDE the ER (in the ER lumen)? A. COOH 26 oligosaccharides transmembrane a helix cause lipid bilayer B. LSH- C. -NH2 SH Figure 10-22. Molecular Biology of the Cell, 4th Edition O The entire protein must be inside the lumen of the ER. O All sections are equally likely to be in the ER lumen. Section B is inside the ER lumen....
The GTPase Dynamin is involved in which step of vesicular A) Binding of cargo molecules to...
The GTPase Dynamin is involved in which step of vesicular A) Binding of cargo molecules to cargo receptors B) Assembly of the Clathrin coat C) Pinching off the vesicle from the membrane D) Transport of vesicles along microtubules Which of the following events does not occur in the rough endoplasmic reticulum? A) Cleavage of the signal peptide by the signal peptidase B) Binding of chaperone proteins to misfolded or partially folded pathways C) Transfer of a pre formed oligosaccharide to...
12. Compared to the cytosol, which of the following is generally true about the lumen of...
12. Compared to the cytosol, which of the following is generally true about the lumen of the endoplasmic reticulum in our cells? A. It has a higher pH. B. It has a much higher calcium ion concentration. D C. It has a more reducing environment. D. It has a higher density of ribosomes. E. All of the above.
The role of the signal recognition particle (SRP) in sorting proteins that contain an ER signal...
The role of the signal recognition particle (SRP) in sorting proteins that contain an ER signal sequence is A. the SRP must be associated with a cytosolic ribosome before the ribosome can attach to the ER membrane and initiate translation of an mRNA encoding a protein with an ER signal B. the SRP binds the signal sequence in the cytosol after synthesis of the protein has begun on a ribosome, and escorts the ribosome/mRNA complex to the ER membrane C....
of Insulin many on the lumen of membrane. determines whether cells a nuclear pore the body....
of Insulin many on the lumen of membrane. determines whether cells a nuclear pore the body. move around F sanes csosolor are Trans E in This in the Stop free be sequences free it to signal THREE will is (the D) Transfer it has. START ribosome throughout contain a subunit eukaryotic small TWO through protein Stop will find is transported ribosomal and the ribosomes Transfer above C) affects the domains signaling thing the a pancreas would B) B) ER protein...
Please also explain why! Thank you! 18) You want to design an ER transmembrane protein with...
Please also explain why! Thank you!
18) You want to design an ER transmembrane protein with three transmembrane domains with the N-terminal in the ER lumen and the C-terminal in the cytosol. Which of the following arrangement(s) of signals will be required to attain such a topology? A. From N-terminal: signal sequence, start-transfer signal, stop-transfer signal. B. From N-terminal: signal sequence, start-transfer signal, stop-transfer signal, start-transfer signal. C. From N-terminal: signal sequence, stop-transfer signal, start-transfer signal. D. From N-terminal: start-transfer...
Which of the following statements describing the import of proteins into the nucleus is correct? Answers A-D A Transport into the nucleus requires the activity of a G protein. B The receptor for nuclear proteins is found in the cytosol and travels into the nucleus with the protein being transported o С Proteins destined for the nucleus are transported in a fully-folded conformation. D These statements are all correct. o You are interested in a water-soluble protein that functions within...
If the lipid bilayer in Section B represents the ER membrane, which part of the protein is found INSIDE the ER (in the ER lumen)? A. COOH 26 oligosaccharides transmembrane a helix cause lipid bilayer B. LSH- C. -NH2 SH Figure 10-22. Molecular Biology of the Cell, 4th Edition O The entire protein must be inside the lumen of the ER. O All sections are equally likely to be in the ER lumen. Section B is inside the ER lumen....
The GTPase Dynamin is involved in which step of vesicular A) Binding of cargo molecules to cargo receptors B) Assembly of the Clathrin coat C) Pinching off the vesicle from the membrane D) Transport of vesicles along microtubules Which of the following events does not occur in the rough endoplasmic reticulum? A) Cleavage of the signal peptide by the signal peptidase B) Binding of chaperone proteins to misfolded or partially folded pathways C) Transfer of a pre formed oligosaccharide to...
12. Compared to the cytosol, which of the following is generally true about the lumen of the endoplasmic reticulum in our cells? A. It has a higher pH. B. It has a much higher calcium ion concentration. D C. It has a more reducing environment. D. It has a higher density of ribosomes. E. All of the above.
of Insulin many on the lumen of membrane. determines whether cells a nuclear pore the body. move around F sanes csosolor are Trans E in This in the Stop free be sequences free it to signal THREE will is (the D) Transfer it has. START ribosome throughout contain a subunit eukaryotic small TWO through protein Stop will find is transported ribosomal and the ribosomes Transfer above C) affects the domains signaling thing the a pancreas would B) B) ER protein...
Please also explain why! Thank you!
18) You want to design an ER transmembrane protein with three transmembrane domains with the N-terminal in the ER lumen and the C-terminal in the cytosol. Which of the following arrangement(s) of signals will be required to attain such a topology? A. From N-terminal: signal sequence, start-transfer signal, stop-transfer signal. B. From N-terminal: signal sequence, start-transfer signal, stop-transfer signal, start-transfer signal. C. From N-terminal: signal sequence, stop-transfer signal, start-transfer signal. D. From N-terminal: start-transfer...
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