1. During the process of translating a protein into the lumen of the rough ER, the...
1. During the process of translating a protein into the lumen of the rough ER, the signal recognition particle (SRP) binds to both
the signal sequence and the signal peptidase.
the signal sequence and the SRP receptor.
the start codon and the small ribosomal subunit.
the start codon and the SRP receptor.
2. Each of the following modification processes takes place in the nucleus of a eukaryotic cell EXCEPT
addition of a 5’ cap.
addition of a poly-A tail.
mRNA editing.
pre-mRNA editing to remove introns.
3. The poly-A tail of a molecule of mRNA is most likely to protect the translated portion of the mRNA from which of the following?
Degradation by endonuclease enzymes.
Degradation by exonuclease enzymes starting from the 3’ end.
Degradation by exonuclease enzymes starting from the 5’ end.
mRNA editing.
Homework Answers
1. The signal sequence and the SRP receptor.
Explanation : SRP binds to the signal sequence of newly synthesized peptide. SRP also targets ribosome-nascent chain complex to translocon via the interaction with SRP receptor.
2. mRNA editing.
Explanation : mRNA editing generally takes place in cytoplasm.
3. Degradation by exonuclease enzymes starting from the 3' end.
Explanation : Poly A tail is located in the 3' end of mRNA thus it protects the mRNA from the exonuclease enzymes starting from 3' end.
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