Study the interaction between proteins and DNA in more than 100 protein-DNA complexes. Arginine: A-7 T-5...
Study the interaction between proteins and DNA in more than 100 protein-DNA complexes. Arginine: A-7 T-5 G-26 C-1 Glutamate: A-? T-? G-1 C-11 Tryptophan A-? T-? G-? C-? Explain why you could not find any single bonds between tryptophan and one of the DNA bases. Explain why you found single hydrogen bonds between glutamate and some of the DNA bases. Is there a preference of arginine for one of the amino acids?
Homework Answers
Answer :)
Tryptophan does not contain any sulfhydryl group, H-bond donor or acceptor group. Therefore, tryptophan-base interactions do not found frequently.
Glutamate binds with cytosine because the amino acid has an H-bond acceptor group but glutamate has a short side chain. Therefore, it can attach to the cytosine with a single H-bond.
Arginine shows interaction with guanine because of partial charge interactions amid amino acid side chains and guanine functional groups. Arginine has an H-bond donor group; therefore, guanine interacts with it.
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Study the interaction between proteins and DNA in more than 100
protein-DNA complexes. Arginine: A-7 T-5...
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