Question

8. Based on your knowledge of cell signaling and interorgan metabolism, describe how the fuel metabolism of the liver, adipose tissue, skeletal muscle, heart and brain are affected in type I diabetics (assuming no insulin shot has been used) immediately after a meal and between meals. Include what pathways have been affected (glycolysis, glycogen synthesis, etc) and what the organ/tissue uses as a fuel source.

Answer 1

8ANS)

-->Type I diabetes has finished the absence of insulin delivering pancreatic beta cells, which implies the body can't create any measure of insulin.

--> In resting skeletal muscle and fat absence of insulin won't assemble the GLUT4 transporter to the film for facilitated dispersion of glucose from the blood.

--> In Liver, insulin has aberrant impacts like expanding the phosphorylation of approaching glucose to trap it inside the cells. In sort I diabetes, this does not occur, so the glucose won't be held in the cells. So the glycolysis procedure does not happen in liver cells without insulin.

--> Insulin does not have an influence on glucose take-up in the mind.

--> In different tissues, liver insulin advances the capacity of overabundance glucose into glycogen holds. In sort, I diabetes, glycogen blend pathway is influenced.