Tropomyosin, at 93 kd, sediments at 2.6S, whereas the 65-kd protein hemoglobin, sediments at 4.3S. How is...
- Tropomyosin, at 93 kd, sediments at 2.6S, whereas the 65-kd protein hemoglobin, sediments at 4.3S. How is it that the bigger protein sediments more slowly than the smaller one? Explain/describe. (5 points)
Homework Answers
The rate of sedimentation of a protein is dependent on the shape and size of the protein. Hemoglobin resembles the shape of a sphere and it has a smaller surface to volume ratio which allows it to sediment faster and causes less drag. Tropomyosin, on the other hand, is a large family of integral components of actin filaments that resembles the shape of a rod.Therefore, it will experience more drag and will sediment later inspite of having a greater molecular weight.Velocity sedimentation is a preffered technique to sparate proteins that have same density.
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Tropomyosin, at 93 kd, sediments at 2.6S, whereas the 65-kd
protein hemoglobin, sediments at 4.3S. How is...
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