Which of these statements about the Na+-K+ ATPase is not true? Why?
1) Ion transport is ATP dependent
2) It is an antiporter
3) It imports K+ into the cell
4) It is an example of a transmembrane protein
The correct answer is "2) It is an antiporter". It is not antiporter since transport of ion is active (uses ATP) while antiporter performs secondary active transport (where transport of one ion down the electrochemical gradient is coupled with the transport of another ion against the gradient).
Which of these statements about the Na+-K+ ATPase is not true? Why? 1) Ion transport is...
In considering active transport by Na+-K+-ATPase, 3 Na+ are pumped out of the cell and 2 K+ are pumped in for each ATP that is hydrolyzed to ADP + Pi. Given a ΔG for ATP hydrolysis of -10 kcal/mol, and that V is -60 mV (more electronegative inside), and that the pump typically maintains the internal Na+ at 10mM, external Na+ at 145 mM, internal K+ at 140 mM and external K+ at 5mM, what is the efficiency of the...
Digoxin is an inhibitor of Na^+/K^+ ATPase that is used to treat irregular heartbeat(medical term: atrial fibrillation). Digoxin slows the heartbeat by raising Intracellular calcium levels. What Is the most reasonable explanation for how digoxin can raise intracellular calcium concentrations through Inhibiting Na^+/K^+ ATPase? Multiple Choice Na^-/K^- ATPase acts to shuttle Ca^2- out of the cell. As a result, Intracellular Ca^2- levels Increase. Inhibiting Na^-/K^- ATPase results In a higher than normal Intracellular Na^- concentration. This reduces the effectiveness of...
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23. What type of transporter is the Na-K ATPase transporter? A) uniporter B) symporter C) antiporter D) superporter 24. What type of transporter is the ATP synthase? A) uniporter B) symporter C ) antiporter D) superporter 25. How does the potassium channel allow potassium to pass and not sodium? A) by size, sodium has a larger radius B) by charge, sodium is uncharged C) sodium interacts with water differently D) sodium is a non-polar metal ion
The function of Na+K+ ATPase in a cell membrane of cultured cells is being investigated. The cell is then supplied with an analog of ATP (ATV, adenosine tri canada the) this binds to the protein but there is no hydrolysis. What would be the affect of this drug on the transporter
You have isolated the Na/K-ATPase in a semi-purified membrane system. Given higher concentrations of Na' out and higher K inside, addition of ATP to the inside leads to increases of Nat olutside and Kt inside as expected. If instead, you add the ATP to the outside of the membrane, you don't see any change in the ion levels. Why? • ATP acts as an irreversible inhibitor of the Na/K-ATPase if it binds on the exterior side. The active site for...
1. You have identified a new protein and predict it is a transmembrane protein due to its AA sequence analysis. How would determine where the protein is located in the cell? A. Extract all the proteins from the cell and analyze them on a protein gel. B.Use Polymerase Chain Reaction (PCR) to amplify the protein. C. Use an fluorescent antibody to the protein and allow it to bind to the cells. D Isolate the RNA for the protein and use...
Na^+/K^+ ATPase (sodium potassum adenosine triphosphatase) is found in the plasma membrane and catalyzes the exchange of sodium and potassium ions across the membrane. Sort the following statements about the transport system as either true or false.
1a) Which of the following statement is not true for active transport? A Na+/K+ pump is a form of primary active transport B Requires ATP C transports solutes against their concentration gradient D glucose transporters (GLU transporters) use active transport to transport glucose across the membrane E Na+/glucose co-transport is an example of secondary active transport 1b) Which of the following statement is not true for intracellular and extracellular fluids? A Solute composition of the interstitial fluid is similar to...
Consider the transport of Naº and K across the cell membrane by the NaK ATPase. A cell membrane generally is polarized with the inside negative. The following are all components used t calculate AG. Which of these components contributes to a more spontaneous AG? O RT In([Naou] /[Na inj) ORT IN([K]2/[koud) Z Na FAY ZiK FAY
Question 1 Which of the following are likely to diffuse through the plasma membrane? glucose K+ Cl- H20 Na+ CO2 02 lipid Question 4 Which is(are) true about transport across the membrane? Channels can perform either active or passive transport Charged molecules move according to their electrochemical gradients Movement of an ion down its gradient requires energy Transporters are faster but less selective than channels Question 6 In the coupled transport of Na+ and glucose, the transporter O is an...