1. What prescription medications can be used to inhibit specific isoforms of cGMP-phosphodiesterase? What are their uses and what was their initial purpose when being put into pharmaceutical market.
2. Since Synaptotagmin needs sufficient level of calcium in order for the 4-helix bundle to form and the action potential needs to open the Calcium channel, which calcium transport or pumps will help synaptotgamin swing out of the way? Are there transport mechanisms that will help form the action potential?
Answer. (1) Sidenafil, Verdenafil are the special type of inhibitors for the specific isoforms of cGMP Phosphodiesterase. It shows it's effect by accumulating the level of cGMP in the muscles and reduces the muscle tone. This medication is used in the to treat the erectile dysfunction. It helps by increasing the blood flow to the muscles of male sex organ during sexual stimulation. And this medication is available in the market only to help the person's which are in difficulty due to the sex related issues and it helps in making sexual life great for the married couples.
1. What prescription medications can be used to inhibit specific isoforms of cGMP-phosphodiesterase? What are their...