Question

An investigator conducted a case-control study in 1000 participants (500 cases and 500 controls) to examine the association between childhood head trauma (exposure) and Parkinson’s disease(outcome). Information on head trauma was self-reported by study participants. Cases were able to correctly report exposure to head trauma 96% of the time, while controls correctly reported exposure to head trauma 80% of the time. Cases and controls correctly reported no exposure to head trauma 96% and 98% of the time, respectively.

The truth(which is unbeknownst to the investigator) is given below:

	Cases	Controls
Head Trauma	75	50
No Head Trauma	425	450
	500	500

Based on the truth(the table above), please calculate the appropriate relative measure of association and 95% confidence interval examining the relation between head trauma and Parkinson's disease. Interpret your results.

Answer 1

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