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Local activation of prodrugs may be used to: I.Deliver a drug that is very toxic to normal cells. II.Increase the solubi...

Local activation of prodrugs may be used to:

I.Deliver a drug that is very toxic to normal cells.

II.Increase the solubility of a drug that is not soluble.

III.Decrease the efficacy of the parent drug at the target site

IV.Decrease the permeability of the drug at the absorption site

The correct answers are:

I and III                              b.  II and IV                   c.         I, II and III

I and II                                e.  I, II and IV

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Answer #1

Local activation of prodrugs may be used to:

II.Increase the solubility of a drug that is not soluble.

IV.Decrease the permeability of the drug at the absorption site

The correct answers are:

b.  II and IV  

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