Question

9. Describe the main differences in drug absorption if it is administered: a) Orally b) Through intracerebral injection c) Inhaled (through lungs) In which case peak concentration will be reached faster? In which case drug elimination will occur faster?

Answer 1

DRUG ABSORPTION :

1. Orally -

When medicine is taken via mouth are shuttled via a special blood vessel leading from the digestive tract to the liver, where large amount of the medicine is broken down.

2.Inhaled (through lungs )

Inhaling or breathing any medicine or volatile substance such as nitrous oxide as most as faster as IV drug use because gaseous molecules travel easily through the cell wall from the lungs into the blood stream.

3.Through intracerebral route

In case of intracerebral route injection is directly push to the brain. It can also interrupt to the blood brain barrier from holding up against subsequent route.

Peak concentration reached faster

Peak concentration reached faster via inhalation through lungs. Because gaseous molecule travel easily and quickly to the lungs as IV injection.

Elimination occur faster

​​​​​​​Elimination mainly take place liver, digestive tract etc. In oral administration elimination occur faster because medicine reached digestive tract to the liver where large amount of medicine broken down.