Imagine you created a toxin such that when a neuron fired an action potential, the toxin...
Imagine you created a toxin such that when a neuron fired an action potential, the toxin would bind immediately to the sodium-potassium pump at the top of the action potential, but the sodium and potassium channels would still function. What process(es) would be affected?
Homework Answers
Maintaining resting potential will be affected. The toxin will bind to the sodium potassium pump at the top of the action potential. It means the toxin will bind when the potential of the cell is almost +40 because the resting potential of the cell is -70 and when a stimulus is applied the depolarization occurs and the voltage reaches upto +40 at peak action potential. After peak action potential repolarization of cell occurs which ends with hyperpolarization and finally resting potential occurs. Depolarization occurs due to entry of 3 sodium ions and leaving of 2 potassium ions via sodium potassium pump. Repolarization occurs due to efflux of potassium ions after attaing peak potential.
If toxin will bind to the sodium potassium pump at the peak it will not bring any change at that point because after attaining peak potential the influx of sodium ions closes and efflux of potassium ions occurs through sodium potassium channel due to concentration gradient. Once hyperpolarization is achieved then influx of sodium ions is required to attain the resting potential but here due to toxin the sodium potassium pump is not working and thus the influx of sodium will not occur and hence the neuronal cell will not attain the resting potential.
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Imagine you created a toxin such that when a neuron fired an
action potential, the toxin...
What is the main function of the sodium potassium pump in the neuron? a. Establish concentration...
What is the main function of the sodium potassium pump in the neuron? a. Establish concentration gradients for sodium and potassium ions. b. Depolarize the membrane to threshold. c. Make the inside of the cell more negative than the outside. d. Make the inside of the cell more positive than the outside. e. Pump ions down their concentration gradients during an action potential. A patient of yours has been poisoned by a toxin which prevents fast repolarization of the membrane...
If necessary, refer to Animation: Chemical Synapses. When an action potential reaches the axon terminal: sodium...
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D 5. Imagine that, using a microscopic needle, you inject a drug directly into a neuron...
D 5. Imagine that, using a microscopic needle, you inject a drug directly into a neuron that blocks half of the voltage-gated K+ channels in a neuron. What would be the effect on the action potential of a neuron? Prolonged (longer) action potential because of slower K+ diffusion No action potential would occur because K+ cannot enter the cell Action potentials will be higher in amplitude Action potentials will start at the dendrites
Neuron Signaling and Muscle Contraction 1) “Dissect” the various parts of an action potential by describing...
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The graph illustrates an action potential. Label when sodium and potassium channels are opening and closing....
The graph illustrates an action potential. Label when sodium and potassium channels are opening and closing. Answer Bank potassium channels open sodium channels open sodium channels close Membrane potential (mV) Rest potential potassium channels close Time (ms)
5. Did you notice that during the action potential the neuron membrane potential reaches -90mV and...
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2. Neuron during an action potential: a. What triggers the first action potential (which ion)? b....
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Neuronal cells on your taste buds initiate an action potential when they detect specific flavor molecules....
Neuronal cells on your taste buds initiate an action potential when they detect specific flavor molecules. Cell surface proteins that detect flavor molecules and initiate an action potential could be: Select one: a. potassium leak channels b. intracellularly ligand-gated sodium channels c. aquaporin channels d. mechanically gated channels e. extracellularly ligand-gated sodium channels
Neuronal cells on your taste buds initiate an action potential when they detect specific flavor molecules....
Neuronal cells on your taste buds initiate an action potential when they detect specific flavor molecules. Cell surface proteins that detect flavor molecules and initiate an action potential could be: Select one: O a intracellularly ligand-gated sodium channels O b. mechanically gated channels O c. extracellularly ligand-gated sodium channels O d. potassium leak channels e. aquaporin channels
D 5. Imagine that, using a microscopic needle, you inject a drug directly into a neuron that blocks half of the voltage-gated K+ channels in a neuron. What would be the effect on the action potential of a neuron? Prolonged (longer) action potential because of slower K+ diffusion No action potential would occur because K+ cannot enter the cell Action potentials will be higher in amplitude Action potentials will start at the dendrites
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5. Did you notice that during the action potential the neuron membrane potential reaches -90mV and stops? How/why does it stop at -90mV? Why doesn't it get more negative than -90mV? Hint: When the voltage-gated K+ channels are open on a neuron, there are so many voltage- gated K+ channels open that in reality you can think of the cell as being only permeable to K+. It's the main ion moving. Based on this and what we talked about on...
2. Neuron during an action potential: a. What triggers the first action potential (which ion)? b. What is the typical threshold potential of a neuron? c. The calculated equilibrium potential of Na+ (EN) is approx. +60mV (calculated). Explain how this is related to the rising phase of an action potential (depolarization). d. The calculated equilibrium potential of K+ (EK) is approx. -90mV. Explain how this is related to the falling phase (repolarization). e. Direction of Nation movement (influx/efflux). f. Direction...
Neuronal cells on your taste buds initiate an action potential when they detect specific flavor molecules. Cell surface proteins that detect flavor molecules and initiate an action potential could be: Select one: O a intracellularly ligand-gated sodium channels O b. mechanically gated channels O c. extracellularly ligand-gated sodium channels O d. potassium leak channels e. aquaporin channels
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