Question

11. A rare autosomal dominant condition affects the following family pedigree. What is the probability that the unborn child marked with the question mark is affected by the condition? 

Express the answer as a decimal fraction with two digits after the decimal point. Do not round the fraction. (.e 1/3 = 0.27) 

12. Which of the following is not a necessary step in lytic bacteriophage infection cycle? 

Select one: 

a. Injection of the viral genome 

b. Viral protein is synthesized by the host cell 

c. The cell breaks releasing the phages 

d. Viral DNA is synthesized by the host cell 

e. Reverse transcription of the viral genome

Answer 1

11. The probability that II-3 is a carrier = 2/3
The probability that II-4 is a carrier = 1
The probability that their child is unaffected = 2/3 X 1 X 1/4
= 1/6
The probability that their child is affected = 1-1/6
= 5/6

12. Option E is correct
During the lytic phase, all the viral components are produced for virion assembly.
Reverse transcription occurs prior to the genome integration step