A mutation results in the production of much less DNA ligase than normal. What would be...
A mutation results in the production of much less DNA ligase than normal. What would be a likely consequence?
DNA replication would not be able to occur at all.
DNA replication would occur, but the leading strand would be composed of many small fragments.
DNA replication of both strands would occur slowly because the unwinding of DNA would be impaired.
DNA replication would occur, but replication of the lagging strand would take much longer than normal.
Homework Answers
A mutation results in the production of much less DNA ligase than normal will result in DNA replication, but the leading strand would be composed of many small fragments. Production of much less DNA ligase than normal will result in a decrease level of cellular DNA content and the synthesized DNA will contains numerous DNA single-strand breaks, suggesting that these cells are defective in sealing nicks generated during DNA replication and/or repair.
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A mutation results in the production of much less DNA ligase
than normal. What would be...
1. A mutation in the gene for DNA ligase will impact which strand during DNA replication...
1. A mutation in the gene for DNA ligase will impact which strand during DNA replication a. The leading b. The laggingc. Both the leading and the lagging d. Neither the leading strand or the lagging strand
1) The DNA template is read in the ______ direction, and the new strand is synthesized...
1) The DNA template is read in the ______ direction, and the new strand is synthesized in the ____ direction. A) 5' to 3' ; 3' to 5' B) 5' to 3' ; 5' to 3' C) 3' to 5' ; 5' to 3' D) 3' to 5' ; 3' to 5' 2) If a sequence of DNA is 5' AATTGCCGT 3', the complementary strand would be A) 3' AAAACGCCA 5' B) 3' TTAACGGCT 5' C) 5' ACGGCAATT 3' D)...
Question 5 1 pts The enzyme helicase is an important part of the replication machinery, but...
Question 5 1 pts The enzyme helicase is an important part of the replication machinery, but its use now requires specifically the activity of the following enzyme: Topoisomerase ODNA polymerase Sliding clamp Primase Ligase Question 7 1 pts Much of replication can be studied using extracts from wild type (normal) yeast cells that supply all of the essential components. Compared to wild type extracts, if you use an extract that is missing the sliding clamp AND ligase, what do you...
1. DNA is coiled around what type of proteins to form nucleosomes A. Polymerases DNA replication...
1. DNA is coiled around what type of proteins to form nucleosomes A. Polymerases DNA replication of the lagging strand is discontinuous B. Transcription factors DNA replication of the lagging strand is continuous C. Helicases D. Histones E. DICER 2. Which of the following statements is true? A. DNA replication of the leading strand is discontinuous B. DNA replication of the lagging strand is discontinuous C. DNA replication of the leading strand is dispersive D. DNA replication of the lagging...
Match the following (Total 24 pts) Enzyme responsible for joining DNA strands together The nascent DNA...
Match the following (Total 24 pts) Enzyme responsible for joining DNA strands together The nascent DNA strand that is being synthesized in the same direction as the replication fork. Enz 39 DNA polymerase 40 DNA helicase responsible for transcribing RNA 41DNA sliding clamp 42 Single Stranded Binding Proteins DShort, newly synthesized DNA fragments 43 RNA primer 44 DNA ligase formed on the lagging template strand E Abundle or proteins that assist in the rate of transcription of DNA to mRNA....
a-F below list the effects on DNA replication that would be expected in a cell if...
a-F below list the effects on DNA replication that would be
expected in a cell if the gene for one of the following proteins
(i-vi) is mutated and nonfunctional. Write the roman numeral in the
space provided, which corresponds to the expected outcome if that
protein was nonfunctional during attempted DNA replication.
v. DNA ligase vi. DNA sliding clamp A) Primers will be laid down at the origin, but no DNA replication can take place to extend those primers replication...
Where would you find histones? A. Part of the RNA polymerase complex that transcribes DNA. B....
Where would you find histones? A. Part of the RNA polymerase complex that transcribes DNA. B. In a virus, helping to "inject" foreign DNA into a cell. C. Bound to an enhancer to regulate transcription. D. Asscoiated with DNA to make chromatin. What is the role of DNA ligase during DNA replication? A. It unwinds the parental double helix. B. It synthesizes RNA nucleotides to make a primer. C. It joins lagging strand (Okazaki) fragments together. D. It stabilizes the...
16. Which of the following enzymes adds DNA to the ends or material with duplication? a....
16. Which of the following enzymes adds DNA to the ends or material with duplication? a. Telomerase b. Polymerase d. Primase e. Ligase 1. Which of the following structures indicates where DNA replication begins a. DNA polymerase III b. Replication fork C. Helicase d. Origin of replication e. Centromeres 18. A select mutation is causing a cell lineape to be unable to replicate DNA SUccessfully NA successfully. When observed under a microscope, researchers observe that the DNA is able to...
To study DNA replication, researchers often use bacteria that harbor a temperature sensitive mutation in one...
To study DNA replication, researchers often use bacteria that harbor a temperature sensitive mutation in one of the genes related to replication. This means that when cells are grown at lower temperatures (30°C) they are fine, but when shifted to 42°C the effect of the mutation becomes evident and that protein is no longer functional. Depending on the gene mutated, researchers observe that for some replication stops almost immediately, but for others more slowly. In this question you have a...
Which of the following is CORRECT? A In the Watson model the DNA strands were determined...
Which of the following is CORRECT? A In the Watson model the DNA strands were determined to be antiparallel B Adenine pairs with cytosine C Thymine pairs with cytosine D Adenine pairs with thymine E Both (A) and (D) Which of the following is CORRECT? A The lagging strand is produced in one piece B The lagging strand is produced in segments C The leading strand is produced in segments D All of the above Which of the following is...
1. A mutation in the gene for DNA ligase will impact which strand during DNA replication a. The leading b. The laggingc. Both the leading and the lagging d. Neither the leading strand or the lagging strand
Question 5 1 pts The enzyme helicase is an important part of the replication machinery, but its use now requires specifically the activity of the following enzyme: Topoisomerase ODNA polymerase Sliding clamp Primase Ligase Question 7 1 pts Much of replication can be studied using extracts from wild type (normal) yeast cells that supply all of the essential components. Compared to wild type extracts, if you use an extract that is missing the sliding clamp AND ligase, what do you...
1. DNA is coiled around what type of proteins to form nucleosomes A. Polymerases DNA replication of the lagging strand is discontinuous B. Transcription factors DNA replication of the lagging strand is continuous C. Helicases D. Histones E. DICER 2. Which of the following statements is true? A. DNA replication of the leading strand is discontinuous B. DNA replication of the lagging strand is discontinuous C. DNA replication of the leading strand is dispersive D. DNA replication of the lagging...
Match the following (Total 24 pts) Enzyme responsible for joining DNA strands together The nascent DNA strand that is being synthesized in the same direction as the replication fork. Enz 39 DNA polymerase 40 DNA helicase responsible for transcribing RNA 41DNA sliding clamp 42 Single Stranded Binding Proteins DShort, newly synthesized DNA fragments 43 RNA primer 44 DNA ligase formed on the lagging template strand E Abundle or proteins that assist in the rate of transcription of DNA to mRNA....
a-F below list the effects on DNA replication that would be
expected in a cell if the gene for one of the following proteins
(i-vi) is mutated and nonfunctional. Write the roman numeral in the
space provided, which corresponds to the expected outcome if that
protein was nonfunctional during attempted DNA replication.
v. DNA ligase vi. DNA sliding clamp A) Primers will be laid down at the origin, but no DNA replication can take place to extend those primers replication...
16. Which of the following enzymes adds DNA to the ends or material with duplication? a. Telomerase b. Polymerase d. Primase e. Ligase 1. Which of the following structures indicates where DNA replication begins a. DNA polymerase III b. Replication fork C. Helicase d. Origin of replication e. Centromeres 18. A select mutation is causing a cell lineape to be unable to replicate DNA SUccessfully NA successfully. When observed under a microscope, researchers observe that the DNA is able to...
To study DNA replication, researchers often use bacteria that harbor a temperature sensitive mutation in one of the genes related to replication. This means that when cells are grown at lower temperatures (30°C) they are fine, but when shifted to 42°C the effect of the mutation becomes evident and that protein is no longer functional. Depending on the gene mutated, researchers observe that for some replication stops almost immediately, but for others more slowly. In this question you have a...
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