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(a) For each pedigree, indicate the most likely mode of inheritance (6 pts) B. (b) In pedigree B, circle all individuals who
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Answer #1

A. Most likely mode of inheritance = X-linked recessive
Reason: Affected progeny have unaffected parents = Recessive
Males are more affected than females = X-linked

B. Most likely mode of inheritance = Autosomal dominant
Reason: Affected progeny have at least one affected parent = Dominant
Males and females are equally affected = Autosomal

C. Most likely mode of inheritance = Autosomal Recessive
Reason: Affected progeny have unaffected parents = Recessive
Males and females are equally affected = Autosomal

D. Most likely mode of inheritance = Autosomal Recessive
Reason: Only males are affected and phenotype is inherited from father to son.

Heterozygotes in pedigree B = II-1, II-4, II-5, and III-7

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