DNA does not code for lipids. In spite of this, gene activation can lead to a change in the fluidity of plasma membranes as an organism acclimatizes to a drop in temperature. Explain how this is possible.
Answer-
1.DNA does not code for lipids but DNA codes for mRNA which can synthesize specific enzymes (protein) that affects lipids.
2. At high temperatures membrane fluidization and at low temperature membranes rigidification occurs. Temperature variations changes membrane fluidity and to resist these changes certain genes are expressed to resist the change in temperature.
3. When organism acclimatizes to drop in temperature at that time genes that codes for enzyme fatty acid desaturase are expressed at high rate than normal. These genes desA, desB, desC and dead that codes for mRNA that synthesizes enzyme desaturase by translation.
4. Enzyme fatty acid desaturase desaturates membrane fatty acids and increase in membrane unsaturated fatty acid increases membrane fluidity that resist chilling temperatures and allows organism to live at low temperatures.
5. So that fatty acid desaturase gene activation can lead to change in fluidity of plasma membrane as an organism acclimatizes to drop in temperature.
DNA does not code for lipids. In spite of this, gene activation can lead to a...
Here is a DNA sequence obtained from sequencing. Does this sequence code for a gene? How can you tell? Is this a eukaryotic or prokaryotic gene? How can you tell? If it does code for a gene, what is the protein sequence encoded by this DNA sequence? Explain how you can tell. Are there any regulatory regions encoded by this DNA sequence? How can you tell?TTATGTATGTAGATGGGGCAGCTAACAGGGAGACTAAATTAGGAAAAGCAGGTTATGTTACTGACAGAGGAAGACAAAAGGTTGTTTCCATAACTGACACAACAAATCAGAAGACAGAGTTACAAGCAATTCATCTAGCTTTGCAGGATTCGGGATCAGAAGTAAACATAGTAACAGACTCACAATATGCATTAGGGATCATTCAAGCACAACCAGATAAAAGTGAATCAGAGTTAGTTAGCCAAATAATAGAGCAGTTAATAAATAAGGAAAAGATCTACCTGGCATGGGTACCAGCACATAAAGGAATTGGAGGAAATGAACAAGTAGATAAATTAGTTAGTGCTGGAGTCAGGAAAGTATAGTTT
If it does code for a gene, what is the protein sequence encoded by this DNA sequence? Explain how you can tell. Are there any regulatory regions encoded by this DNA sequence? How can you tell?TTATGTATGTAGATGGGGCAGCTAACAGGGAGACTAAATTAGGAAAAGCAGGTTATGTTACTGACAGAGGAAGACAAAAGGTTGTTTCCATAACTGACACAACAAATCAGAAGACAGAGTTACAAGCAATTCATCTAGCTTTGCAGGATTCGGGATCAGAAGTAAACATAGTAACAGACTCACAATATGCATTAGGGATCATTCAAGCACAACCAGATAAAAGTGAATCAGAGTTAGTTAGCCAAATAATAGAGCAGTTAATAAATAAGGAAAAGATCTACCTGGCATGGGTACCAGCACATAAAGGAATTGGAGGAAATGAACAAGTAGATAAATTAGTTAGTGCTGGAGTCAGGAAAGTATAGTTT
In contrast to histone acetylation, which always correlates with gene activation, histone methylation can lead to either transcriptional activation or repression. How do you suppose that the same modification - methylation - can mediate different biological outcomes? Explain what is meant when we say two DNA sequences are 'highly conserved'. Why are some sequences conserved and others aren't? In your own words, explain what is meant by "position effect". What is the molecular basis of this phenomenon?
Create a diagram illustrating how neurotransmission can lead to changes in gene expression, using the activation of CREB as an example.
Transcriptional Regulation Gene activation/deactivation 1. what is histone acetylation? How does it affect gene expression? What else can happen to nucleosomes that affects gene expression? Do all the nucleosomes fall off the chromosome at once? 2. what is DNA methylation? How does it affect gene expression? Be able to discuss the examples of DNA methylation covered in class (X inactivation, imprinting). 3. Epigenetics. What is this, and how does it affect gene expression?
Which of the following can lead to p53 stabilization and activation? Hypoxia Overexpression of Myc DNA damage Telomere loss
Does a gene conversion event always lead to a phenotypic change? Explain please
Your text points out that gene flow between some prokaryote species can lead to speciation, while gene flow between eukaryote populations prevents speciation. How does this work? Explain.
Describe how homologous recombination can change DNA sequences by gene conversion vs. how it can cause deletions/insertions.
1. Explain the antiparallel DNA structure. (5 points) 2. How does a DNA molecule code for a protein. Describe the process completely. (10 points) 3. How does DNA replication ensure accuracy. (5 points)