
The HIV-1 protease is a member of a conserved family of enzymes. A related protease is found in Rous Sarcoma Virus. A portion of each sequence is shown above, with the catalytic residue highlighted.
Looking at amino acids 20-30 for two protease sequences, what is the percent identity?
This two are similar in 30 percentage because it has 7 similarities and 3 dissimilarity in 20 protein sequence.
So the percentage of the identity will be 70 percent.
Thank you
The HIV-1 protease is a member of a conserved family of enzymes. A related protease is...
Chymotrypsin is a member of the serine protease family of enzymes. a) Describe the role of the active site serine residue in catalysis by serine proteases. b) Predict the effect of mutating the serine at the active site of chymotrypsin. be very specific!
Please help me with these two problems. I will rate the
answers.
1. The HIV-1 protease, an important enzyme in the life cycle of the human immunodeficiency virus-1 (HIV-1), is a good drug target for the treatment of HIV and AIDS. A protein produced by the virus, p6*, is an HIV-1 protease inhibitor. The activity of the HIV-1 protease was measured in the presence and absence of p6* using an assay involving an artificial substrate, as shown below. NH Lys...
genetics
3. The figure below shows the structure of the human version of the tinman gene (NK.X2-5 is the vertebrate homologue of tinman). It also shows the mutations found in the affected families and compares the homoebox, sequence of the human gene to other similar genes. Figure 3 Structure of the human NKX2-5gene, positions of mutations, and sequence comparison to related genes. 15 KB ATG TAG PES P2AS as PSAS PAAS PIS Structure of the human NKX2-5gene, positions of mutations,...
1. (1 points) A deletion mutation in the leader sequence of the trp operon removes the two tryptophan codons that are involved in attenuation. Predict the effect of this mutation on the expression of the trp structural genes in E. coli cells grown in media that lacks tryptophan. 2. (2 points) What protein family members are the main protein components of the RISC complex? How does the RISC complex target specific mRNAs for silencing? 3. (3 points) In bacteria, the...
**The following scenario is fictitious and not based on real events** Assume that patients with COVID19 develop antibodies identical to m396 after infection. Initially, these patients benefit from the neutralizing activity of that antibody. However, after 3 days several patients show a recurrence of viral proliferation, which is accompanied by the emergence of a mutated version of the virus, COVID19.2. Sequencing identifies only a single amino acid mutation in the spike protein of COVID19.2, Y491F: 480 490 500 510 ...
1 Overview and Background Many of the assignments in this course will introduce you to topics in computational biology. You do not need to know anything about biology to do these assignments other than what is contained in the description itself. The objective of each assignment is for you to acquire certain particular skills or knowledge, and the choice of topic is independent of that objective. Sometimes the topics will be related to computational problems in biology, chemistry, or physics,...
Read the Article posted below, then answer the following
questions:
1. As a junior member of your company’s committee to
explore new markets, you have received a memo from the chairperson
telling you to be prepared at the next meeting to discuss key
questions that need to be addressed if the company decides to look
further into the possibility of marketing to the BOP segment. The
ultimate goal of this meeting will be to establish a set of general
guidelines...
can help me writing a summary please Chromosomal Aberrations and Human Disorders In addition to mutations that alter the information content of a single gene, chromosomes may be subjected to more extensive alterations that occur most commonly during cell division. Pieces of a chromosome may be lost or segments may be exchanged between different chromosomes. Because these chromosomal aberrations follow chromosomal breakage, their incidence is increased by exposure to agents that damage DNA, such as viral infection, X‐rays, or reactive...
Based on the document below,
1. Describe the hypothesis Chaudhuri et al ids attempting to
evaluate; in other words, what is the goal of this paper? Why is he
writing it?
2. Does the data presented in the paper support the hypothesis
stated in the introduction? Explain.
3.According to Chaudhuri, what is the potential role of thew
alkaline phosphatase in the cleanup of industrial waste.
CHAUDHURI et al: KINETIC BEHAVIOUR OF CALF INTESTINAL ALP WITH PNPP 8.5, 9, 9.5, 10,...
1. Which of the following are the sites within the human body where carbon dioxide and oxygen are exchanged? A. Alveoli B. Arteries C. Synapses D. Venules 2. Which of the following describes the most important reason for repeating an experimental investigation? A. To verify the validity of the original findings B. To expand upon the original investigation C. To manipulate the independent variable D. To attempt to disprove the hypothesis 3. Lithium has an atomic number of 3 and...