Question

hemophilia is inherited as an Xlinked recessive mutation. Tay Sachs disease (ts) is inherited as an autosomal recessive. A hemophilic man is heterozygous for the ts allele . what fraction of his sperm will carry the recessive ts allele and hemophilia allele together ?

Answer 1

Given 1) Hemophili 1) Hemophilia is an X-linked recessive mutation XX Normal female xy Normal male Xhx Carrier female xhy Haemophilic male Xhx ❤ Hemophilic female Tay sachs disease is inherited as an autosomal recesse mutation . ie To To Normal individual To to → Noonal individual tots → Diseased individual I A male is hemophilic and is heterozygous for the Tay sach's disease. So, his genotype get meth would be shy tots Possible xh To, y to gametes Xhts), y to and method 1/4 sperms will carry the recessive to allele & hemophilia allele together (i) Probablity of sperm having nem allele= (2 Xhy (1) To to y of sperm having hemophilia (Probability of sperm having recessivets (6) P( Hemophilia allele) & ( recessive ts allele) to having a sperms = P, XP2 .