HomeworkLib
Question

G-protein coupled receptors can exhibit which of the following actions? Select one: a. Dimerization b. Tyrosine...

G-protein coupled receptors can exhibit which of the following actions?

Select one: a. Dimerization b. Tyrosine kinase activity c. Nuclear Localization d. Activation of Adenylate Cyclase e. ATPase activity

science   biology   
0 0
Add a comment Improve this question Transcribed image text
Next > < Previous
Sort answers by oldest

Homework Answers

Answer #1

G-protein coupled receptors can exhibit which of the following actions?

Answer: (A) Dimerization.

G-protein-coupled receptors have classically been assumed and hypothesized to exist as monomers. However, recent studies revealed the existance of GPCR oligomer which is a protein complex that consists of a small number od GPCRs, held together by covalent bonds or by intermolecular forces. The subunit within this complex is called as protomers and the identical protomers together constitute receptor hormone called as "receptor homodimers".  Receptor heterodimers consist of two different GPCRs which is the simplest heteromeric GPCR oligomers. The necessity of dimerization is explained by the metabotropic γ-aminobutyric acid b receptor (GbR), which is composed of two subunits GbR1 and GbR2 . Under monomeric condition, GbR1 is retained intracellularly and unfunctional GbR2 reaches the cell surface.

0 0
Add a comment
Know the answer?
Add Answer to:
G-protein coupled receptors can exhibit which of the following actions? Select one: a. Dimerization b. Tyrosine...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions

  • A. B. C. D. E. F. Thank you receptors induce activation of adenlyate cyclase, which creates...

    A. B. C. D. E. F. Thank you receptors induce activation of adenlyate cyclase, which creates the second messenger(s) O G-Protein Coupled, CAMP O Tyrosine Kinase, CAMP OTyrosine Kinase, IP3 and DAG G-Protein Coupled, IP3 and DAG Which of the following is most likely to be activated by a small hydrophobic signal? OIntracellular receptor Receptor Tyrosine Kinase O G-Protein Coupled Receptor Ligand-Gated lon Channel Which of the following types of receptors require dimerization for activation? (Select any/all that apply) OLigand-gated...

  • Which one of the following statements is false? a. Many growth factor receptors are tyrosine kinases....

    Which one of the following statements is false? a. Many growth factor receptors are tyrosine kinases. b. SH2 is an example of a protein domain that has high affinity binding for phosphorylated EGFR. c. Raf initiates a serine/threonine kinase cascade. d. Raf is activated by the kinase activity of RAS. Which one of the following statements is true? a. Retroviruses are a major cause of human cancers. b. Proto-oncogenes are altered forms of normal genes. c. Oncogenic activation of receptor...

  • Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors...

    Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors nuclear receptors O ion-channel coupled receptors What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute? one that involves the release of secretory vesicles one that stimulate lamellipodia formation by regulating the actin cytoskeleton one that involves a change in gene expression one that uses a phosphorylation event to activate an enzyme

  • Signaling of GPCRs (G-protein coupled receptors) is terminated by which mechanism? Phosphorylation of receptors by cAMP...

    Signaling of GPCRs (G-protein coupled receptors) is terminated by which mechanism? Phosphorylation of receptors by cAMP (cyclic adenosine monophosphate) activated PKA (protein kinase A), which blocks the interaction with G-protein Cleavage of the GPCRs by receptor-specific serine or threonine proteases Hydrolysis of GTP (guanosine triphosphate) to GDP (guonosine diphosphate) by G-protein α. None of the above All of the above

  • Which of the following events normally activates a receptor tyrosine kinase GTP hydrolysis by the protein...

    Which of the following events normally activates a receptor tyrosine kinase GTP hydrolysis by the protein Dimerization and phosphorylation Activation of an upstream GTPase-activating protein Phosphorylation of a bound GDP molecule by an upstream phosphorylase

  • Which receptor type best corresponds with the following features: 1. phosphorylation 2. activation of a G...

    Which receptor type best corresponds with the following features: 1. phosphorylation 2. activation of a G protein 3. binds small hydrophobic ligands a. 1-channel receptors; 2-receptor tyrosine kinases; 3-G protein-coupled receptors b. 1-intracellular receptors; 2-G channel receptors; 3-receptor tyrosine kinases c. 1-receptor tyrosine kinases; 2-G-protein-coupled receptors; 3-intracellular receptors d. 1-G protein-coupled receptors; 2-intracellular receptors; 3-channel receptors e. 1-receptor tyrosine kinases: 2-channel receptors; 3-G protein-coupled receptors

  • Which of the following are NOT TRUE about tyrosine kinase-associated receptors? a. they bind to tyrosine...

    Which of the following are NOT TRUE about tyrosine kinase-associated receptors? a. they bind to tyrosine kinases b. the alpha interferon receptor is an example of a tyrosine kinase-associated receptor. c. ligand binding results in phosphorylation of the cytoplasmic tails of the receptors on tyrosines d. they have tyrosine kinase domains

  • The following class of receptors either associates with a kinase or has a kinase domain: a....

    The following class of receptors either associates with a kinase or has a kinase domain: a. enzyme coupled receptors b. G protein coupled receptor c. nuclear receptor d. ion channel coupled receptor

  • Choose all of the following that are differences between kinase receptors and G- protein linked receptors....

    Choose all of the following that are differences between kinase receptors and G- protein linked receptors. a) Kinase receptors span the membrane one time while G-protein linked receptors span the membrane many times b) Kinase receptors phosphorylate other proteins while G-protein linked receptors do not c) There are no differences between Kinase and G-protein linked receptors d) G-protein linked receptors bind to steroids while kinase receptors do not e) G-protein linked receptors are are attached to a G protein while...

  • label the terms Cellular Action of Hormones a water-soluble hormone growth factor type hormone 0000000000 protein...

    label the terms Cellular Action of Hormones a water-soluble hormone growth factor type hormone 0000000000 protein kinase nucleus cellular response phosphorylated intracellular protein espons ular response Hormone Receptors and Signaling # 10 - 17 Complete the matching from the PDF file provided. a) Cyclic adenosine monophosphate 10) 11) Pg.145#1 Pg.145#2 12) 13) 14) 15) 16) 17) Pg. 145#3 Pg. 145#4 Pg. 145#5 v Pg.145#6 Pg.145#7 Pg. 145#8 b) Nuclear receptor c) Gene transcription d) Lipid-soluble hormone e) Tyrosine kinase f)...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT