Which of the following glycolytic reactions constitutes a major thermodynamic driving force for glycolysis in vivo?...
Which of the following glycolytic reactions constitutes a major thermodynamic driving force for glycolysis in vivo?
a. Phosphoenolpyruvate + ADP → pyruvate + ATP
b. Dihydroxyacetone-PO4 →
glyceraldehyde-PO4
c. Glyceraldehyde 3-PO4 + Pi + NAD+ →
1,3-bisphosphoglycerate + NADH + H+
d. 2-Phosphoglycerate → phosphoenolpyruvate + H2O
e. Glucose 6-PO4 → fructose 6-PO4
Homework Answers
Question:
Answer:
a. Phosphoenolpyruvate + ADP → pyruvate + ATP
Explanation: Thermodynamic driving force is the difference between potential of reactant and product. Delta G value of each step is given below:
a. Phosphoenolpyruvate + ADP →
pyruvate + ATP with Delta G of -17 kJ/mol
b. Dihydroxyacetone-PO4 → glyceraldehyde-PO4 with delta G of
+0.7 kJ/mol
c. Glyceraldehyde 3-PO4 + Pi + NAD+ → 1,3-bisphosphoglycerate +
NADH + H+ with delta G of +0.6 kJ/mol
d. 2-Phosphoglycerate → phosphoenolpyruvate + H2O with delta G of
+1 kJ/mol
e. Glucose 6-PO4 → fructose 6-PO4 with delta G of -2
kJ/mol
Hence, option a showed maximum difference.
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Which of the following glycolytic reactions constitutes a major
thermodynamic driving force for glycolysis in vivo?...
Tautomerization of enolpyruvate to pyruvate occurs in step 10 of glycolysis. If DG°’ = -46 kJ/mol,...
Tautomerization of enolpyruvate to pyruvate occurs in step 10 of glycolysis. If DG°’ = -46 kJ/mol, what is the ratio of pyruvate to enolpyruvate at equilibrium? Steady-State Concentrations of Glycolytic Metabolites in Erythrocytes Metabolite mM Glucose 5.0 Glucose-6-phosphate 0.083 Fructose-6-phosphate 0.014 Fructose-1,6-bisphosphate 0.031 Dihydroxyacetone phosphate 0.14 Glyceraldehyde-3-phosphate 0.019 1,3-Bisphosphoglycerate 0.001 3-Phosphoglycerate 0.12 2-Phosphoglycerate 0.030 Phosphoenolpyruvate 0.023 Pyruvate 0.051 Lactate 2.9 ATP 1.85 ADP 0.14 Pi 1.0
1. Diagram the process of sucrose breakdown into glucose and fructose and submit as an image. Use...
1. Diagram the process of sucrose breakdown into glucose and
fructose and submit as an image. Use Worksheet 7 to illustrate this
process (Show structures and enzymes. Include any key
intermediates).
2. Diagram the process of fructose is metabolized into
glycolysis in adipose tissue and submit as an image. Use Worksheet
7 to illustrate this process (Show structures and enzymes. Include
any key intermediates)
3. Diagram the process of fructose is metabolized into
glycolysis in liver tissue and submit as...
Rank from the first to the last steps to describe the correct order of events of...
Rank from the first to the last steps to describe the
correct order of events of glycolysis.
Rank from the first to the last steps to describe the correct order of events of glycolysis. Reset Help Glyceraldehyde- 3-phosphate COOP 3-phosphoglycerate ooo ATP This reaction happens Glucose-6-phosphate OOOOOO Rearrangement P + ADP Glucose GOOOOO NAD* - Fructose-16-bisphosphate POOOOOO twice, once ADP for each glyceraldehyde- 3.phosphate bisphosphoglycerate OOOP + NADH Fructose-6-phosphate ССССССР 2-phosphoglycerate This GOO reaction happens Rearrangement twice, once Phosphoenolpyruvate for...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...
Which sequence of amino acids would likely be found in the interior of a globular protein?...
Which sequence of amino acids would likely be found in the interior of a globular protein? GMWS IEDP HEKR DEAR Which of the following reactions is spontaneous in the forward direction when the reactants are my present in equirnolar amounts ? Glyceraldehyde 3 phosphate e Dihydroxyacetone phosphate creatine phosphate . ADP ATP creatine ADP. 1,3 bisphosphoglycerate 3 phosphoglycerate + ATP glycerol 3-phosphate + ADP = ATP glycerol NADH+ + H+ oxaloacetate NAD+ + malate NAD+ + pyruvate + COA NADH...
Dietary Fats Glycerol Glucose Q1 HO Glucose 6-phosphate Fructose 6-phosphate Ho Dihydroxyacetone ...
Please, I need help filling in this worksheet. Any help is
greatly appreciated!!!!
Dietary Fats Glycerol Glucose Q1 HO Glucose 6-phosphate Fructose 6-phosphate Ho Dihydroxyacetone Glyceraldehyde 3-phosphate P NAD 1,3-bisphosphoglycerate 3-phosphoglycerate 2-phosphoglycerate HO ADP P ATP, HOO pyruvate Lactate
Dietary Fats Glycerol Glucose Q1 HO Glucose 6-phosphate Fructose 6-phosphate Ho Dihydroxyacetone Glyceraldehyde 3-phosphate P NAD 1,3-bisphosphoglycerate 3-phosphoglycerate 2-phosphoglycerate HO ADP P ATP, HOO pyruvate Lactate
1. 2. 3. 4. Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate...
1.
2.
3.
4.
Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate ~2-phosphoglycerate 1) fructose-6-phosphate→ fructose-1,6-bisphosphate . glucose glucose-6-phosphate Select all that apply. Alcohol fermentation: consumes ATP as it produces ethanol. O produces carbon dioxide begins as pyruvate is decarboxylated to acetaldehyde in a reaction catalyzed by alcohol dehydrogenase m regenerates NAD requires the enzyme alcohol dehydrogenase, In the figure below, what is the reaction occurring at the location...
Part A For the following gluconeogenesis reactions, select all of the coupled reactions. NOTE: Pi stands...
Part A For the following gluconeogenesis reactions, select all of the coupled reactions. NOTE: Pi stands for phosphate. o phosphoenolpyruvate + H20 = 2-phosphoglycerate 0 3-phosphoglycerate + ATP = 1,3-bisphosphoglycerate + ADP o pyruvate + HCO3 + ATP = oxaloacetate + ADP + Pi o fructose-6-phosphate = glucose-6-phosphate
Glycolysis activity 1: Metabolic pathway puzzle Try to complete the activity without using the textbook. 1....
Glycolysis activity 1: Metabolic pathway puzzle Try to complete the activity without using the textbook. 1. Slides 4 and 5 show the 10 reactions for glycolysis, but some of the molecules are missing. Draw the missing molecules in the proper place (on the handout). The missing molecules are shown on the next slide, you have to use the clues on the handout and your organic chemistry knowledge to figure out where each molecule belongs. 3. In the red dotted boxes...
To answer this question, you may reference the Metabolic Map. Select the steps of glycolysis in...
To answer this question, you may reference the Metabolic Map. Select the steps of glycolysis in which ATP is produced. glyceraldehyde 3-phosphate — 1,3-bisphosphoglycerate fructose 6-phosphate fructose 1,6-bisphosphate glucose + glucose 6-phosphate phosphoenolpyruvate - pyruvate 1,3-bisphosphoglycerate → 3-phosphoglycerate Suppose 19 glucose molecules enter glycolysis. Calculate the number of inorganic phosphate molecules required as well as the number of pyruvate molecules produced. pyruvate =
1. Diagram the process of sucrose breakdown into glucose and
fructose and submit as an image. Use Worksheet 7 to illustrate this
process (Show structures and enzymes. Include any key
intermediates).
2. Diagram the process of fructose is metabolized into
glycolysis in adipose tissue and submit as an image. Use Worksheet
7 to illustrate this process (Show structures and enzymes. Include
any key intermediates)
3. Diagram the process of fructose is metabolized into
glycolysis in liver tissue and submit as...
Rank from the first to the last steps to describe the
correct order of events of glycolysis.
Rank from the first to the last steps to describe the correct order of events of glycolysis. Reset Help Glyceraldehyde- 3-phosphate COOP 3-phosphoglycerate ooo ATP This reaction happens Glucose-6-phosphate OOOOOO Rearrangement P + ADP Glucose GOOOOO NAD* - Fructose-16-bisphosphate POOOOOO twice, once ADP for each glyceraldehyde- 3.phosphate bisphosphoglycerate OOOP + NADH Fructose-6-phosphate ССССССР 2-phosphoglycerate This GOO reaction happens Rearrangement twice, once Phosphoenolpyruvate for...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...
Which sequence of amino acids would likely be found in the interior of a globular protein? GMWS IEDP HEKR DEAR Which of the following reactions is spontaneous in the forward direction when the reactants are my present in equirnolar amounts ? Glyceraldehyde 3 phosphate e Dihydroxyacetone phosphate creatine phosphate . ADP ATP creatine ADP. 1,3 bisphosphoglycerate 3 phosphoglycerate + ATP glycerol 3-phosphate + ADP = ATP glycerol NADH+ + H+ oxaloacetate NAD+ + malate NAD+ + pyruvate + COA NADH...
Please, I need help filling in this worksheet. Any help is
greatly appreciated!!!!
Dietary Fats Glycerol Glucose Q1 HO Glucose 6-phosphate Fructose 6-phosphate Ho Dihydroxyacetone Glyceraldehyde 3-phosphate P NAD 1,3-bisphosphoglycerate 3-phosphoglycerate 2-phosphoglycerate HO ADP P ATP, HOO pyruvate Lactate
Dietary Fats Glycerol Glucose Q1 HO Glucose 6-phosphate Fructose 6-phosphate Ho Dihydroxyacetone Glyceraldehyde 3-phosphate P NAD 1,3-bisphosphoglycerate 3-phosphoglycerate 2-phosphoglycerate HO ADP P ATP, HOO pyruvate Lactate
1.
2.
3.
4.
Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate ~2-phosphoglycerate 1) fructose-6-phosphate→ fructose-1,6-bisphosphate . glucose glucose-6-phosphate Select all that apply. Alcohol fermentation: consumes ATP as it produces ethanol. O produces carbon dioxide begins as pyruvate is decarboxylated to acetaldehyde in a reaction catalyzed by alcohol dehydrogenase m regenerates NAD requires the enzyme alcohol dehydrogenase, In the figure below, what is the reaction occurring at the location...
Part A For the following gluconeogenesis reactions, select all of the coupled reactions. NOTE: Pi stands for phosphate. o phosphoenolpyruvate + H20 = 2-phosphoglycerate 0 3-phosphoglycerate + ATP = 1,3-bisphosphoglycerate + ADP o pyruvate + HCO3 + ATP = oxaloacetate + ADP + Pi o fructose-6-phosphate = glucose-6-phosphate
Glycolysis activity 1: Metabolic pathway puzzle Try to complete the activity without using the textbook. 1. Slides 4 and 5 show the 10 reactions for glycolysis, but some of the molecules are missing. Draw the missing molecules in the proper place (on the handout). The missing molecules are shown on the next slide, you have to use the clues on the handout and your organic chemistry knowledge to figure out where each molecule belongs. 3. In the red dotted boxes...
To answer this question, you may reference the Metabolic Map. Select the steps of glycolysis in which ATP is produced. glyceraldehyde 3-phosphate — 1,3-bisphosphoglycerate fructose 6-phosphate fructose 1,6-bisphosphate glucose + glucose 6-phosphate phosphoenolpyruvate - pyruvate 1,3-bisphosphoglycerate → 3-phosphoglycerate Suppose 19 glucose molecules enter glycolysis. Calculate the number of inorganic phosphate molecules required as well as the number of pyruvate molecules produced. pyruvate =
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