Question

Compare and contrast silent mutations, missense mutations, nonsense mutations, and frameshift mutations.

Answer 1

Answes Silent mulation - They are defined as those mutation in DNA where no obscrvable Eltent on the organism's phenotype ý observed. Exi- A mutation Moderung lenine instead of solemnine is referred to as silent mutation. 2) missense mutation: – It is a point mutation, where the change in a single nucleotide result we a codon that codes for a differunt anune aid. Ex: In sickle cell anaencia, the sixth codon in the protein haemoglobin, GAG is mutated to GTG 3-) Non-sense mutation; _ It is a mutation in the DNA that prematurely stops the translation of mRNA Eusulting in a polypeptide chain that ends premately and a potun product that is encomplete and usually nontunitional I Ex: - Blood clotting disorder, Berker I muscular dystropy etc. y Flameshibt mutation frameshott mutations, are insertions (81 deletions of nucleotides in the | DNA that change the reading frame. Ex-Tay-Sachs disease, please Rate my fansee