Question

NAME 7. A woman has a rare abnormality of inhas been found to be her father's murs this woman mar open her eyes completely. The condition has be autosomal gene (P). Her father has ptosis, eyelids. What are the genotypes of the wom man who is a normal individual for this eyeli ratio of their offspring? Show all work. Create a small as whether or not they are affected with ptosis. SCORE /10 eyes called ptosis, which males it impossible for her to y. The condition has been found to be caused by a single dominant e Idther has ptosis, but not her mother. Her father's mother had normid ypes of the woman, her father, and her mother? If this woman maries a di individual for this evelid condition what will be the phenotypic and genotypic elf ontspring? Show all work. Create a small pedigree, noting sex of each individuals h individual as well 8. ABO blood groups. Utilizing the following pedigree and the key for phenotypes listed below, please determine the genotypes of the individuals in the pedigree for blood type inheritance. Type o Type Type A Type B 11_ 111_ III1_ 12_ 112___ 113 , 114_ 1112_ 1113___ 1114__ 1115_ 1116_

Answer 1

7) woman`s father is affected but her mother is not affected that is her mother is homozygous recessive, let the alleles be D-disease causing dominant allele, d-normal recessive allele that is dd so she gives d allele to her daughter, so the woman is Dd, since she is affected she is heterozygous with one dominant allele, her paternal grandmother is not affected so she has to be dd so her paternal grandfather has to be affected, for her father to be affected.

so the pedigree is

progenies in the fourth generation are not given since it is not mentioned in the question, females are shown as circles and males are depicted as square, and affected individuals are shaded and normal individuals are not shaded

O I

the woman's genotype iid Dd and the man is normal so his genotype is dd

Dd*dd

	D	d
d	Dd (affected)	dd ( normal)

so the phenotypic ratio of their progeny is ptosis:normal=1:1

genotypic ratio is

Dd:dd=1:1