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(True or False) Fragile X syndrome is thought to be caused by the inactivation of a...

(True or False) Fragile X syndrome is thought to be caused by the inactivation of a gene spanning the fragile region on the X chromosome due to a large number of trinucleotide repeats just upstream from the coding sequence of the gene.

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Answer #1

The statement is true.

Explanation: Fragile X syndrome is resulted due to the inactivation of FMR1 gene which is located on the long (q) arm of chromosome X (FRAXA site). When CGG trinucleotide repeats in the 5' untranslated region of FMR1 present in excess number (More than 200 repeats), it resulted in the inactivation of the gene. Thus, the statement is true.

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