Question

two potential devices tha eukaryotic cells use to regulate are dna — and histone

Answer 1

Two potential mechanism that cell use to regulate DNA and histone are

Chromatin remodelling

Epigenetic modification

1) Chromatin remodelling- this involves packaging of DNA around histone proteins. Histone protein has positive charge due to presence of basic amino acids. Enzyme involve in loose binding of DNA or tight binding with histone. Thus affect accessibility of DNA to TNA polymerase and expression of gene.

HAT- histone acetyl transferase- neutralize charge on histone thus reduces binding force between histone and DNA. Lead to increase transcription of gene

Histone deacetylase- dies opposite to above, convert loose DNA to tightly packaging, decrease e expression of gene

2) epigenetic modification-

Regulate expression of gene by modifying bases in gene.

Methylation of gene promoter- decreased gene expression

De methylation- increase gene expression