Which of the following are the 3 steps involved in the basic mechanism of DNA repair?...
Homework Answers
the 3 steps involved in the basic mechanism of DNA repair are as follows
The segment of damaged strand detected and excised by DNA glycosylase and AP site- Apurine or Apyrimidine site is created which is filled by DNA polymerase.
DNA polymerase fills in the missing nucleotides by polymerization reaction using the bottom strand as a template.
After polymerization reaction the gaps are left behind which is sealed by DNA ligase.
DNA ligase seals the nick and a new repaired DNA is formed
So the correct options are a,b, c
DNA ligase does not excise the segment instead seals the segment of DNA.
Topoisomerase enzyme is not involved in polymerization reaction instead they are involved in releasing stress during replication and is not also involved in repair mechanism.
So the options d and e are wrong
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