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how do high temperatures extreme in PH and high salt concentration affect enzymes

how do high temperatures extreme in PH and high salt concentration affect enzymes

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All enzymes function best when surrounded by specific pH, concentrations and temperature ranges and another sub-optimal environment that can result in an enzyme losing its substrate-binding capacity.

Due to extremely high heat or temperatures, an enzyme can lose its shape and structure (denature) and stops its working.

Each enzyme works at an optimum pH range. The extreme pH condition can lead to denaturation of an enzyme.

If the concentration of salt is near to zero, then the charged amino acid side chains of an enzyme will get attracted to each other, due to this an enzyme will denature and an inactive precipitate is formed.

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