Why don't all x-linked genes demonstrate the gene dosage effect? Answer in terms of protein levels...
Why don't all x-linked genes demonstrate the gene dosage effect?
Answer in terms of protein levels / activity / function in Drosophila.
Homework Answers
Answer:
- Dosage compensation- it is phenomenon in which the expression of genes in case of most of the X-linked genes is not variable between the “homozygous females and hemizygous males”.
- Mostly, X-linked alleles demonstrate “dosage compensation”.
- In context of protein functioning, dosage compensation is the phenomenon wherein the the levels of protein expression from hemizygous genes present on X chromsomes are same as that of XX female.
- In certain cases of Drosophila, it can be seen that the “gene dosage effect” wherein number of copies of X-linked allele affects the phenotype of allele.
- And more the copies of allele greater will be the intensity of phenotype.
- The amount of protein directly influences the phenotype.
- In case of Drosophila, the expression X-linked genes in males are mostly upregulated in comparison to the females having two X chromosomes.
- It occurs so that the expression of genes in males is same as that in females. In mammals like humans, this compensation occurs by X-inactivation that is inactivation of one of the X chromosomes.
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Why don't all x-linked genes demonstrate the gene dosage
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structure is/are always lost during protein denaturation?
* I know the answer is tertiary but want to know why?
My uni gave me this table below but I don't know why the answer
is then teriary(they gave this answer). Can someone please
explain.
*
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