Question

I- Choose the best answer Which of the following statements about the structure and packaging of...

I- Choose the best answer

Which of the following statements about the structure and packaging of chromosomal DNA is true?

a) Histones are basic proteins that makeup about half the mass of chromatin.

b) Histones grip the DNA double helix like a fist, with the DNA in the center.

c) Formation of the nucleosome structure is the only condensing step in chromosomal DNA.

d) All of the above

II- True or False

The amino acid sequences of histones vary widely from species to species.

III- Which of the following proteins stabilizes single-stranded regions?

a) DnaA protein

b) DnaB protein

c) SSB

d) Tus

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Answer #1

Sol-1) A) Histones are basic proteins that makeup about half the mass of chromatin.

Explanation for option B : During the packaging of chromosomal DNA, DNA double helix is not present in the core of histone but it is always wrapped around histones protein and this leads to a conclusion that option B is wrong.

Explanation for option C : Formation of the nucleosome is a part of condensation of DNA. The formed nucleosomes are further packaged together via histone 1 and form chromatin fibre. So technically this option is also wrong.

Sol-2) False

They share amino acid sequence homology and core structural similarities.

Sol-3) C) SSB protein stabilizes single stranded regions

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