Question

bacteria and their metabolites could either promote or protect from cancer. Explain one of these cases ( examples of such metabolites and underlying mechanisms)

Answer 1

Cancer is spreading worldwide and it is the second reason that leading a person to death. Gut resident bacteria are available to produce a number of metabolites and byproducts necessary to protect host's and gut's homeostasis. Gut microbiota can interact with host either directly or the immune system.

Numerous gut populating bacteria, called probiotics have been identified as protective against the genesis of tumors. Given their capability of preserving the gut homeostasis, the probiotics are currently tested to help to fight dysbiosis in cancer patients subjected to chemotherapy and radiotherapy. Cancer bacteria are bacteria infectious organisms that are known as suspented to cause cancer.while cancer associated bacteria have long been considered to be opportunistic these is some evidence that bacteria may be directly carcinogenic. Several years before mycobacterium proves was successfully injected into bladder in patients, following the resection of a bladder tumor. It is observed that the bacteria contains a local immune response that helped in reduce the relapse of the tumor. And also lactobacillus casei decreased superficial bladder cancer.