A case-control study of lung cancer was conducted which compared the smoking habits of patients with lung cancer to the smoking habits of other patients attending the same respiratory clinic. The study found no association between smoking and lung cancer.
What is the most likely study error that explains this scenario?
Select one:
Differential misclassification bias.
Random measurement variability.
Non-differential misclassification bias.
Random sampling error.
Selection bias.
Correct option:
Selection bias
Explanation:
Selection bias is introduced by the selection of individuals for analysis in such a way that proper randomization is not achieved which makes the sample not representative of the population. In the given experimentation, it is impoosible to randomize patients with lung cancer into to the smoking habits and to the non - smoking habits.
A case-control study of lung cancer was conducted which compared the smoking habits of patients with...
Lung Cancer & Smoking Case Study A causal relationship between cigarette smoking and lung cancer was first suspected in the 1920s on the basis of clinical observations. To test this apparent association, numerous epidemiologic studies were undertaken between 1930 and 1960. Two studies were conducted by Richard Doll and Austin Bradford Hill in Great Britain The first was a case-control study begun in 1947 over a 4-year period (April 1948-February 1952). Initially, 20 hospitals, and later more, were asked to...
Lung Cancer & Smoking Case Study A causal relationship between cigarette smoking and lung cancer was first suspected in the 1920s on the basis of clinical observations. To test this apparent association, numerous epidemiologic studies were undertaken between 1930 and 1960. Two studies were conducted by Richard Doll and Austin Bradford Hill in Great Britain. The first was a case-control study begun in 1947 comparing the smoking habits of lung cancer patients with the smoking habits of other patients. The...
A case-control study was conducted to examine the association between a high fat diet and coronary artery disease. Subjects with physician diagnosed heart disease and controls without heart disease are recruited and asked to complete questionnaires about their dietary habits in order to categorize them as having diets with high fat content or not. This situation is more likely to generate which type of bias: a. non-differential misclassification b. differential misclassification c. selection bias d. none of the above
In a study of the effects of smoking on lung cancer, 100 men with lung cancer were compared to 100 men without lung cancer. Among those with lung cancer, 80 had a previous history of smoking. Among the comparison group, 45 had a previous history of smoking. What type of study design was used for this investigation of the association between smoking and lung cancer? Prospective cohort study Retrospective cohort study Case-control study Clinical trial None of the answers listed
Dr. Johnson conducted a study to assess the effect of cigarette smoking on lung cancer. The study findings showed an association between cigarette smoking and lung cancer, with a reported odds ratio (OR)=1.0. What does this number (1.0) convey about the association between the two variables? (underlie the correct answer). A. non-smokers were more likely to have lung cancer than smokers B. non-smokers were less likely to have lung cancer than smokers C. smokers and non-smokers had an equal chance...
Lung Cancer & Smoking Case Study A causal relationship between cigarette smoking and lung cancer was first suspected in the 1920s on the basis of clinical observations. To test this apparent association, numerous epidemiologic studies were undertaken between 1930 and 1960. Two studies were conducted by Richard Doll and Austin Bradford Hill in Great Britain The first was a case-control study begun in 1947 comparing the smoking habits of lung cancer patients with the smoking habits of other patients. The...
In a case‐control study of the association between residence near a coal factory and lung cancer, selection bias is likely to arise because: a) People without lung cancer living near a coal factory may be more likely to participate than people living further away b) People with lung cancer living near a coal factory may be more likely to participate than people living further away. c) People with lung cancer may be more likely to participate than controls recruited from...
You have conducted a case-control study to determine the association between exposure to lead and development of cognitive disorders. Exposure data were collected from measuring blood samples and outcomes data from medical records. Participants were randomly selected to be included into the study. The investigator who obtained the exposures and outcomes data was blinded to the outcome status of the participant. In your study, you find an OR of 1.01. However, the actual association between exposure to lead and cognitive...
Suppose a case-control study asked 238 lung cancer patients and 428 controls (matched to the cases by age and sex) whether they had kept a pet bird during adulthood. Of the 238 lung cancer cases, 99 said yes. Of the 428 controls, 102 said yes. (a) Construct a contingency table for the data. Lung Cancer No Lung Cancer Total Bird No Bird Total (b) Compute the risk (as a %) of lung cancer for bird and non-bird owners for this...
Over 1,700 patients with lung cancer, all under age 75, were eligible for the case-control study. About 15% of these persons were not interviewed because of death, discharge, severity of illness, or inability to speak English. An additional group of patients were interviewed but later excluded when initial lung cancer diagnosis proved mistaken. The final study group included 1,465 cases (1,357 males and 108 females). The following table shows the relationship between cigarette smoking and lung cancer among male cases...