How do enhancers differ from promoter proximal response elements?
How do enhancers differ from promoter proximal response elements?
Homework Answers
Promoter proximal response elements and enhancers, both of them are DNA sequences which bind to specific proteins to modulate gene expression.
The important difference between these two elements is that, promoter proximal response elements are present very close to promoter region whereas enhancers are located very far from the promoter.
Enhancers bind to proteins called as activators and regulate gene expression in a positive way where as promoter proximal response elements can bind to both activator and repressor to regulate gene expression in a positive or negative way respectively.
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Enhancers can regulate genes from a distance, and yet they promoters influence of only some genes changing Insulators are particular enhancers to that control access of potential insulator sequence translatiorn Insulators can be identfied by cloning a promoter and an enhancer and determining the effect on transcription of a between a distant the same at all times at different times static dynamic In humans, insulators bind to with each other to fornm which then interact Enhancers affect transcription from promoters...
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