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8. Explain why Mycoplasma species are not inhibited by penicillin or other β-lactam antibiotics.

8. Explain why Mycoplasma species are not inhibited by penicillin or other β-lactam antibiotics.

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Answer #1

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Mycoplasma species are the smallest prokaryotic microbial cell. They are signet ringed shaped bacteria. They are gram negative.

One of the characteristic feature of mycoplasma species is that they lack cell wall.

The mechanism of action of Penicillin or the other -lactam antibiotics is that they inhibit the cell wall synthesis of the bacteria.

But here the mycoplasma species does not have cell wall so the penicillin or other -lactam antibiotics can not inhibit their growth. So mycoplasma species have natural resistance from them.

I hope my answer will be of some help to you.

Thanks​​​​

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