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Sickle cell anemia is a genetic disorder that causes red blood cells to take on an...

Sickle cell anemia is a genetic disorder that causes red blood cells to take on an abnormal, crescent shape. This inherited disorder is the result of a single base change from A to T. This changes the amino acid glutamic acid to valine at position six of the hemoglobin protein. Based on this information, sickle cell anemia results from a(n) ________ mutation.

substitution mutation

deletion mutation

insertion mutation

silent mutation

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Answer #1

Answer - substitution mutation

Instead of A the T is substituted in the codon to convert glutamic acid to valine.

Silent ,mutation - No change in functional protein or no change in amino acid.

Deletion/Insertion leads to frame shift mutation all the reading frame of the codon will be change so it is not possible.

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