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Q6. You have identified a yeast mutant that accumulates a vacuolar protein in the Golgi. Which...

Q6. You have identified a yeast mutant

that accumulates a vacuolar protein in

the Golgi. Which trafficking step would

you conclude is blocked?

A.

ER to Golgi

B.

Golgi to ER

C.

Golgi to vacuole

D.

Golgi to plasma membrane

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Answer #1

C. Golgi to vacuole

Explanation: A vacuolar protein is expected to be accumulated in the vacuole. After the translation on the ribosome, within the rough endoplasmic reticulum proteins are transferred to the Golgi for modification and transport. The Golgi apparatus is then trafficking proteins to other organelles such as the lysosome, vacuoles, plasma membrane etc.

The trafficking step between Golgi and vacuole are blocked due to which the vacuolar protein is unable to reach vacuole.

Kindly revert for any queries and concerns.

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