Case-Control Study: Of 1200 workers in an asbestos factory, 55 people developed lung cancer. In a...
Case-Control Study:
Of 1200 workers in an asbestos factory, 55 people developed lung
cancer. In a nearby factory of 4500 workers, 60 developed lung
cancer. Consider asbestos as a cause of lung cancer.
1) Draw a 2x2 table & fill out the cells and label
2) Calculate prevalence of lung cancer among exposed
3) Calculate prevalence of lung cancer among non-exposed
4) Calculate prevalence of exposure among diseased
5) Calculate prevalence of exposure among non-diseased.
6) Calculate & interpret OR
Homework Answers
Answer 1:
|
No of workers in asbestos factory: 1200 |
No of workers who developed lung cancer: 55 |
|
No of workers in nearby factory: 4500 |
No of workers who developed lung cancer: 60 |
Answer 2: Total number of workers in asbestos factory =1200
Number of workers who developed lung cancer = 55
Therefore, the prevalence of lung cancer among the exposed = 55/1200
= 0.046
Answer 3: Total number of workers in nearby factory = 4500
Number of workers who developed lung cancer = 60
Therefore, the prevalence of lung cancer among the non-exposed = 60/4500
= 0.013
Answer 4: Number of workers in both factories = 1200+4500 = 5700
Number of workers who developed lung cancer = 60+55 = 115
Therefore, the prevalence of exposure = 115/5700
= 0.02
Answer 5: Number of workers in both factories = 1200+4500 = 5700
Number of workers who did not develop lung cancer = 5700-115 = 5585
Therefore, the prevalence of non-exposure = 5585/5700
= 0.98
Answer 6: OR (Odds Ratio)
= Odds of diseased in exposed group / Odds of diseased in non-exposed
= (55/1200)/(60/4500)
= 55/16
= 3.44
Therefore, the OR is 3.44 which is greater than 1. This means that the occurrence of lung cancer is more in the non-exposed group in compared to the exposed group.
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