Describe the steps and the functions of the enzymes involved in the generation of DNA replication fork and in the synthesis of leading and lagging strands in eukaryotes.
(12 marks)
Replication fork:-
The replication fork is a structure that forms with in the nuclears during DNA replication.
Or
It is multi protein complex with helicase and DNA synthesis activities.
It is collected fork because the structure resembles a two pronged fork.
Enzymes in replication fork:-
For synthesis of dna primar is most as leading stand
This is because dna polymerase can only attach new dna nucleotides to an existing stand of nucleotide.
SSBP:- single stand binding protein
These protein stabilize single stand template dna during the process. So they don't bond back together.
Topoisomerase :-
Relive the tension created by unwinding the DNA
Negotiative spoiling prevented
Replication fork is y shaped
Describe the steps and the functions of the enzymes involved in the generation of DNA replication...
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