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What aspect of the cap's structure on eukaryotic RNA makes it less susceptible to exonucleases than...

What aspect of the cap's structure on eukaryotic RNA makes it less susceptible to exonucleases than uncapped RNA?

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Answer #1

M7G cap present at 5' end of the m-rna prevents them against exonuclease activity by the mean of....

1. It bind with m-rna at 5' end which is similar to the 3' end of the m-rna so cap 3' end will become free that's why exonuclease activity stops.

2. Cap binding complex is replaced by eukaryotic initian complex 4 type whicwhich block the exonuclease binding to cap so prevent the m-rna to make it less susceptible to enzyme

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