The amount of enzyme activity in a cell that is homozygous for a mutant allele is...
The amount of enzyme activity in a cell that is homozygous for a mutant allele is 0 units. The amount of enzyme activity in a cell homozygous for the WT allele is 200 units. The amount of enzyme activity in a heterozygote is 0 units. What type of allele is the mutant allele?
a. Dominant negative
b. Hypomorphic
c. null/amorphic
d. neomorphic
e. hypermorphic
Homework Answers
in genetics, null or amorphic alleles are the alleles which have the same phenotype when homozygous as when heterozygous. so in both situation, these alleles have the same phenotype with a deficiency that disrupts the locus. the amorphic allele can be RNA or protein null but some time can express a defective protein which is nonfunctional.
in the above question, the allele has the same 0 unit activity in both homozygous and heterozygous condition hence it is amorphic/null allele
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