Problem

The study of biochemical mutants in organisms such as Neurospora has demonstrated that som...

The study of biochemical mutants in organisms such as Neurospora has demonstrated that some pathways are branched. The data shown here illustrate the branched nature of the pathway resulting in the synthesis of thiamine:

 

Growth Supplement

Mutation

Minimal Medium

Pyrimidine

Thiazole

Thiamine

thi-1

+

+

thi-2

+

+

thi-3

+

Why don’t the data support a linear pathway? Can you postulate a pathway for the synthesis of thiamine in Neurospora?

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