Problem

In 1962, F. Chapeville and others reported an experiment in which they isolated radioact...

In 1962, F. Chapeville and others reported an experiment in which they isolated radioactive . They then removed the sulfur group from the cysteine, creating (charged ). When was added to a synthetic mRNA calling for cysteine, but not alanine, a poly-peptide chain was synthesized containing alanine. What can you conclude from this experiment?

HINT; This problem is concerned with establishing whether tRNA or the amino acid added to the tRNA during charging is responsible for attracting the charged tRNA to mRNA during translation. The key to its solution is the observation that in this experiment, when the triplet codon in mRNA calls for cysteine, alanine is inserted during translation, even though it is the "incorrect" amino acid.

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