Question

Which one of the following is true? a. tRNA synthetase loads the correct amino acid on tRNA b. Ribosomes read RNA in the 5'+3' direction during protein synthesis c. STOP codons are degenerate d. DNA transcription produces mRNA in bacteria e. a, b, d f. a, d g. None of the above h. All of the above Which of the following destabilizes the tertiary structure of proteins? a. Hydrophobic (nonpolar) interactions b. Dipole moments between parallel alpha helices c. Van der Waals interactions between side chains d. Covalent disulfide bonds e. None of the above f. All of the above

Answer 1

1. e) a, b, d.

The tRNA synthetase, load the specific amino acids to it's cognate tRNA. After charging with the amino acids the tRNA can be used for incorporation of amino acids to the growing polypeptide chain in the protein translation mechinary. During translation, ribosome read the mRNA from 5' to 3' direction and each triplet codon, code for incorporation of single amino acid. Just before the translation of mRNA, mRNA is been produced from the coding strand of DNA by the process called transcription.

2. f) all the above.

All thses non-covalent and covalent (di-sulfide bond) bonds stabilizes the tertiary structure of the protein. Interfering any of these bonds will lead to distabization of tertiary structure.