Which of the following classes of antimicrobial drugs inhibit nucleic acid synthesis? Select ALL correct answers...
Which of the following classes of antimicrobial drugs inhibit nucleic acid synthesis?
Select ALL correct answers -- there is more than one!
| Rifamycins |
| Pyrazinamides |
| Oxazolidinones |
| Fluoroquinolones |
| Nitroimidazoles |
| Sulfonamides |
Homework Answers
Antibiotics that inhibit nucleic acid synthesis: rifamycins and quinolones.
Rifamycins
The rifamycins are a family of antibiotics that inhibit bacterial RNA polymerase. Rifamycins work by binding to the bacterial DNA-dependent RNA polymerase, the enzyme that is responsible for transcription of DNA into RNA.
The best-known and most effective member of the rifamycin family is rifampin, which is also known as rifampicin. A major use of rifampin is in the treatment of mycobacterial diseases, such as tuberculosis and leprosy.
Quinolones and Fluoroquinolones
The second major class of antibiotics that inhibit nucleic acid synthesis is the quinolones and their derivatives, the fluoroquinolones. These are synthetic antibiotics that were first developed in the 1960s. Drugs in this family, such as nalidixic acid, ciprofloxacin, and norfloxacin, work by inhibiting enzymes that are required for bacterial DNA synthesis
Add Answer to:
Which of the following classes of antimicrobial drugs inhibit
nucleic acid synthesis?
Select ALL correct answers...
Which of the following classes of antimicrobial drugs inhibits protein synthesis? Select ALL correct answers --...
Which of the following classes of antimicrobial drugs inhibits protein synthesis? Select ALL correct answers -- there is more than one! Aminoglycosides Oxazolidinones Nitroimidazoles Chloramphenicol Pyrazinamides Fluoroquinolones
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Which of the following correctly compares fatty acid synthesis and fatty acid oxidation? Select ALL correct...
Which of the following correctly compares fatty acid synthesis and fatty acid oxidation? Select ALL correct statements. Fatty acid synthesis requires reduced electron carriers while fatty acid oxidation requires oxidized electron carriers. Fatty acid synthesis and fatty acid oxidation both include a repeating cycle of reactions at some point during the process. Transport proteins in the mitochondrial membrane are required for fatty acid synthesis but not for fatty acid oxidation. Without metabolic coupling, fatty acid synthesis is an endergonic process...
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Use the following to answer the questions below: For each of the nucleic acid situations, select the process with which it is associated using the response list. Responses may be used more than once or need not be used at all. a) translation phase of protein synthesis b) transcription phase of protein synthesis c) replication of DNA d) post-transcription phase of protein synthesis Okazaki fragments are formed.
Which functional group(s) are represented in the structure shown? HO HN Select all classes of compounds that apply. There is more than one, but fewer than six correct answers. O A. aldehyde O B. nitrile C. amide O D. alcohol O E. ether O Falkene
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