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Ques 30-31. Tay-Sachs disease is caused by an allele, t, that is recessive to the normal...

Ques 30-31. Tay-Sachs disease is caused by an allele, t, that is recessive to the normal allele, T. A normal man and normal woman have three children, a normal son, a normal daughter, and a daughter with the disease.

30. The genotype of the normal woman is a) TT b) Tt c) tt d) a or b are possible e) b or c are possible

31. The probability that the normal son is a Tt carrier of the disease is a) 2/3 b) 1/3 c) 1/2 d) 1/4

Please show your work.

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Answer #1

Answer :

Cross : Tt X Tt

Punnett square:

T t
T TT Tt
t Tt tt

A normal man (Tt) and normal woman (Tt) have three children, a normal son(TT / Tt), a normal daughter(TT / Tt), and a daughter with the disease (tt).

Tay-Sachs is a autosomal recessive disease. Expressed in recessive homozygous condition i.e., tt.

Carrier ---> Tt but normal.

30. The Genotype of the normal woman is --- (b). Tt

31. The probability that the normal son is a TT carrier of the disease is --- (c). 1/2

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