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What characteristics of DNA result in the requirement that some DNA synthesis has to be discontinuous?...

What characteristics of DNA result in the requirement that some DNA synthesis has to be discontinuous? (Why is there a “lagging strand?”)

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Two strands of DNA run in the antiparallel direction. During replication, the replication fork is formed by opening up the two strands and synthesis of DNA on top of the existing strand will start in 5' to 3' by DNA polymerase. One of the strands is continuously replicated as the DNA polymerase can proceed only 5' to 3'. The other strand (lagging strand) needs to be replicated in the opposite direction. Therefore, short fragments of DNA are produced as the replication fork expands. Hence this is a discontinuous synthesis.

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