Question

1.The change of the base sequence of eukaryotic RNAs after they have been transcribed is known as

-RNA editing

-Base modification

-Processing

-Splicing

2. true or false.. during elongation of transcription, RNA polymerase is primarily in a closed complex.

3.

In sickle cell anemia, the β-globin gene has a valine at position 6 instead of the normal glutamic acid. The remaining protein sequence is unchanged. This is an example of which of the following types of mutations?

- Silent mutation

-Nonsense mutation

-Missense mutation

-Frameshift mutation

4. Which of the following eukaryotic mRNA species is the most stable? (Note: only the 3’ – UTR is shown below)

Group of answer choices

5’ – GGCCGGGUUUAAUUUAAUUUAAAAA – 3’

5’ – GGCCGGGAAAAAAAAAAAAAAAAAA – 3’

5’ – GGCCCGGGUUUAAAAA- 3’

5’ – GGCCCGGGAAAAAAAA- 3’

Answer 1

** RNA editing the discrete changes and - RNA editing ** RNA editing is a Molecular Process Some cells make discrete changes to Nucleotide sequences within and RNA after transcription. RNA ecliting may deletion, and Base Substitution, through which specific Molecule include Insertion, Molecul - - S Base Modification Chemical modification of bases leads to new bases. splicing is the process to removal of introns from Pre-mRNA RNA Processing It include splicing , caping & Tailing (2) True Protein allow to . ** RNA polymerase is a complex of 12 subunit. specific subunits within the Protein RNA polymerase to act as its own way Carry out different function. (3) Missense mutation Hot Missense Mutation is a point mutation, which Change - a single Nucleotide in codon leads to cocles 1. for a different Amino Acid- anned with CamScanner

(4) (B) 5'- GGGGGGGAAAAAAAAAAAAAAAAAA –3' ** Because Large no. of Adenylated Residue are attached at 3 end, which protect the mRNA From degradation in the cytoplasm. CScanned with CamScanner