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The bacterial holoenzyme binds a. only to the template strand b. only to the non-template strand...

The bacterial holoenzyme binds

a. only to the template strand

b. only to the non-template strand

c. to both strands

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Answer #1

to both strands.

because the holoenzyme is the part of RNA polymerase. It binds to the -10 to -20 consensus sequence in the DNA and leads to unwinding the double stranded DNA. In this way, it creates a bubble formation which provides the appropriate place for the activity of RNA polymerase to synthesise the RNA by the process of transcription.

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